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EVestG

EVestG
evestg
EvestG

EVestG is a new diagnostic technique that measures the patterns of electrical activity in the brain’s vestibular (or balance) system allowing Doctors to dramatically fast-track the detection of mental and neurological illnesses. Correctly diagnosing mental illness is a massive problem Worldwide and some say this is the best invention ever to come out of Monash University.

About the Inventor

Brian Lithgow, Senior lecturer, Electrical and Computer Systems Engineering. Brian’s research interests include Neurological, Neurodegenerative and Vestibular diagnostics and modeling particularly related to Parkinsons, Scizophrenia, Depression and Meniere's diseases.

Jayashri Kulkarni commenced her appointment as Professor of Psychiatry, The Alfred and Monash University in 2002. She directs a large psychiatric research group, the Monash Alfred Psychiatry Research Centre (MAPrc), with approximately 119 staff and students. The Centre is dedicated to discovering new treatments, new understanding and new services for people with a range of mental illnesses.

Jayashri Kulkarni completed her MBBS degree in 1981 at Monash University and worked mainly in Emergency Medicine before deciding to specialise in Psychiatry. She became a Fellow of the Royal Australian and New Zealand College of Psychiatrists in 1989 and was awarded a PhD from Monash University in 1997 for her thesis “Women and Psychosis”. Jayashri has pioneered the novel use of estrogen as a treatment for schizophrenia and is internationally acknowledged as a leader in the field of reproductive hormones and their impact on mental health.

Inspiration

Brian Lithgow saw the diagnostic potential of measuring and comparing different patterns of electrovestibular activity because the brain’s vestibular system is closely connected to the primitive regions of the brain that relate to emotions and behaviour. By measuring the patterns of electrical activity in the brain’s vestibular against distinct response patterns found in depression, schizophrenia and other CNS disorders, Lithgow was able to develop electrovestibulography, which is sort of like an “ECG for the mind”.
Working with Jayashri and other psychiatry researchers at Monash University's Alfred Psychiatry Research Centre (MAPrc), he tested volunteers and found distinct response patterns, or "biomarkers", that distinguished different CNS diseases from each other and from regular electrovestibular activity.
How it works

Electrovestibulography (EVestG) is a new diagnostic tool/system which allows for a visualisation of the vestibular signal. As the vestibular system is sensitive to fluctuations in neurotransmitter levels, EVestG has shown potential to evaluate not only vestibular disorders (e.g. Meniere’s Disease and Benign Paroxysmal Positional Vertigo) but a range of other neuropsychiatric disorders (including depression and bipolar disorder).
At this stage, EVestG biomarkers are being discovered / “mined” /calibrated from the brainwaves of people already diagnosed with mental or nerve conditions compared with age and gender match healthy controls. These biomarkers correlations have sensitivities and specificities of 90% with their primary diagnosis and are available within the 45 minutes it takes to process the signal through a computer. This time should be compared to the current time taken clinical diagnosis which can take over 5 years in many conditions; some such as Alzheimer’s can only be diagnosed post mortem.
Other links
Autism visible in brain scans
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